[11C]Choline

Commercially available: ready to use consumables and optimized method

Application

[11C]Choline is a PET diagnostic radiotracer used in oncology and in particular for prostate cancer. Because of its low uptake in normal brain, heart and urinary tract tissues compared to other tracers like [18F]FDG, imaging tumors located near those structures results in a greater sensitivity.

 

Configuration

This 11C process automated on a disposable device from target outlet to final product vial involves a “Reagent Kit” and a “Cassette”. The process runs on AllinOne model AIO-18 (and any higher model).

Advantages

  • 11C chemistry made simple
  • Whole process on one box
  • Reproducible yield
  • No lab bench preparation required
  • Disposable cassette, no cleaning

Performances

Cassette and reagents set up time < 1 min
Synthesis time 15 min
Typical production yield 33 ± 4% decay un-corrected
Radiochemical purity ≥ 98 %