[18F]FET

Commercially available: ready to use consumables and optimized method

Application

18F-FET, an L-tyrosine amino acid analog, is a neuro-oncologic PET agent used in the evaluation of patients with primary brain tumors. 18F-FET PET performs much better than 18F-FDG PET for the diagnosis of such primary brain tumors. Furthermore, 18 F-FET PET imaging also improves disease monitoring by early identification of tumor recurrence and progression.

Configuration

This process can operate on AiO 18 HPLC

Advantages

  • High yield >= 35% ndc
  • Process suitable for commercialization
  • Formulation requires no compounding prior injection
  • Plug and play consumables including HPLC eluents
  • No laboratory bench work preparation
  • Same 18F source as FDG

Performances

Cassette and reagents set up time < 1 min
Synthesis time 50 min
Typical production yield

40 +/- 5 % ndc

Radiochemical purity > 98%