[18F]DCFPyl

Under MTA

Application

18F-DCFPyl is a fluorine-18 labelled ligand binding specifically to PSMA. Developed by Johns Hopkins University (JHU), it allows imaging of prostate cancer and clear-cell renal-cell carcinoma (CCRCC).

Configuration

The preparation of 18F-DCFPyl has been implemented jointly by Trasis and JHU on the AllinOne automated synthesizer. The process uses a cassette and a reagent kit.

The AllinOne AIO24 model (or higher) built-in with radio-HPLC is suitable for 18F-DCFPyl process.

Advantages

  • State-of-the-art yield 
  • No lab bench preparation
  • Ready for use consumables
  • Reduced operator exposure 

Performances

Cassette and reagents set up time < 1 min
Synthesis time 60 min
Typical production yield 30-35% decay un-corrected
Radiochemical purity ≥ 95