[18F]UCB-H

Commercially available: ready to use consumables and optimized method

Application

[18F]UCB-H is a fluorine-18 labelled ligand that binds specifically to the Synaptic Vesicle Glycoprotein 2A (SV2A). SV2A plays a central role in the mechanisms underlying neurotransmission, and its PET imaging with [18F]UCB-H provides insight into the synaptic density in the brain.

Configuration

The AllinOne AIO-18 HPLC model (or higher) is suitable for the [18F]UCB-H process.

 

Advantages

  • State-of-the-art yield
  • No lab bench preparation
  • Ready to use consumables
  • Reduced operator dosimetry

Performances

Cassette and reagents set up time < 1 min
Synthesis time 50 min
Typical production yield 30 - 35% decay un-corrected
Radiochemical purity ≥ 97 %