[68Ga]-labelled peptides: DOTA NOC, DOTA TOC, DOTA TATE, PSMA HBED

Commercially available: ready to use consumables and optimized method

 

Application

68Ga-labeled peptides are PET imaging tracers mainly used in oncological indications. Various kind of tumors can be differentiated depending on the peptide’s properties.

Configuration

68Ga-labelled peptides can be obtained on Trasis radio-synthesizers miniAllinOne and AllinOne. The process requires a cassette and a reagent kit per batch in order to radio-label peptides following a specific automated process.

Advantages

  • Single process compatible with several generators. It allows to swap generator suppliers without change in the process
  • High yield, optimized process
  • Stable and injectable formulation
  • Plug and play, all accessories included
  • No laboratory bench preparation

Literature

[68Ga] peptide high-output production on commercially available MiniAIO synthesizer

Performances

Cationic prepurification

Cassette and reagents set up time < 1 min
Synthesis time 19 min
Typical production yield 65 - 80% decay un-corrected
Radiochemical purity ≥ 98%

 

Without prepurification

Cassette and reagents set up time < 1 min
Synthesis time 15 min
Typical production yield 70 - 80% decay un-corrected
Radiochemical purity ≥ 98%