UCB-H

UCB-H is a small-molecule high-affinity SV2A ligand serving as the precursor for [18F]UCB-H, which binds specifically to synaptic vesicle glycoprotein 2A across excitatory and inhibitory synapses.

This PET tracer quantifies synaptic density loss in neurodegenerative diseases, epilepsy, and psychiatric disorders by providing whole-brain distribution with fast kinetics and high specific binding.
Synthesis set avalaible for:

• [18F]UCB-H